Anti-emetics - Metoclopramide, Domperidone, Ondansetron, Cyclizine.

Chapter 1

Physiology

Open Question

Act of vomiting


1) What is the vomiting centre, and where is it located in the brain?

2) What is the chemoreceptor trigger zone (CTZ), and where is it  located in the brain? What receptors are there in the CTZ?

3) Does the vomiting centre only receive input from the CTZ?

Factors involved in the control of vomiting. Adapted from Fig 25.5 Rang, Dale, Ritter and Flower. Pharmacology 6th Edition, 2007, Elsevier Limited.